Genital Angiokeratomas in Adult Men and Women: Prevalence and Predisposing Factors.

Introduction: There is a paucity of prevalence data for genital angiokeratomas in adults. The objective of this article is to determine prevalence of genital angiokeratomas in adults as a function of sex, age, and race/ethnicity.

Methods: A cross-sectional study was conducted over 11 months during 2013 and 2014 using a convenience sample of adult men and women consenting to genital examination during melanoma screening and surveillance by a senior dermatologist in an outpatient clinic.

Prevalence and Gross Morphologic Features of Perianal Melanocytic Nevi.

Importance: The presence of numerous melanocytic nevi is a significant melanoma risk factor, but there are scant data related to prevalence and morphologic features of melanocytic nevi in the perianal area. The prognosis of perianal melanoma is often dismal because of hidden location and diagnosis delay.

Objective: To determine prevalence and morphologic features of perianal melanocytic nevi.

Cutaneous melanoma: preoperative tumor diameter in a general dermatology outpatient setting.

Background: The ABCD mnemonic for cutaneous melanoma indicates that tumor diameter (D) is typically greater than 6 mm.

Objective: To determine the distribution of preoperative tumor diameter in a midwestern United States general dermatology practice-based case series.

Methods: Patient records were reviewed for preoperative maximal tumor diameter for primary cutaneous melanomas diagnosed between January 1, 2006, and February 1, 2012.

Guanfacine-induced lichenoid drug eruption in a child with autism and attention deficit hyperactivity disorder.

Lichenoid drug eruptions (LDEs) have a variety of medication causes. We report a case of a 5-year-old boy with autism and attention deficit hyperactivity disorder treated with guanfacine who developed pruritic lesions consistent with LDEs. Rechallenge was not attempted.

A case of blue rubber bleb nevus syndrome with gastrointestinal and central nervous system involvement.

Blue rubber bleb nevus syndrome, or Bean syndrome, is a rare sporadic disorder of venous malformations of the skin and internal viscera. We report a rare case of blue rubber bleb nevus syndrome with gastrointestinal and central nervous system involvement.

Hypothalamic-pituitary-adrenal axis suppression related to topical glucocorticoid therapy in a child with psoriatic exfoliative erythroderma.

Exfoliative erythroderma is a rare presentation of psoriasis in children and adults. We report a 9-year-old girl with exfoliative erythroderma secondary to plaque-type psoriasis who developed hypothalamic-pituitary-adrenal axis suppression resulting from topical treatment with a medium-potency glucocorticoid. This case emphasizes the need for awareness of this potentially life-threatening complication of topical glucocorticoid use, particularly in patients who have significant compromise of barrier function secondary to widespread skin disease.

Prognostic usefulness of sentinel lymph node biopsy for patients who have clinically node negative, localized, primary invasive cutaneous melanoma: a Bayesian analysis using informative published reports.

Objective: To assess the prognostic value of sentinel lymph node biopsy status for patients with localized, clinically node negative, primary invasive cutaneous melanoma.

Design: Predictive value of positive or negative sentinel lymph node biopsy (SLNB) results for melanoma-related death, using raw numbers from informative publications.

Setting And Participants: Reports comprising 50 patients with cutaneous melanoma who had undergone SLNB, based on PubMed search (January 1, 1993, through June 3, 2010).

Acral melanocytic nevi: prevalence and distribution of gross morphologic features in white and black adults.

Objective: To determine prevalence and morphologic features of acral melanocytic nevi in white and black adults.

Design: Point prevalence survey.

Setting: Outpatient dermatology clinic.

Cutaneous melanoma and intervention strategies to reduce tumor-related mortality: what we know, what we don't know, and what we think we know that isn't so.

The care of patients who have cutaneous melanoma (CM) has undergone a dramatic change during the past five decades. In an increasing majority of cases, CM is being discovered in a premetastatic phase of tumor progression. Most patients are being treated in the ambulatory setting with a minimum of inconvenience and economic cost, and modest re-excision margins have largely replaced the mutilating surgical exonerations that were once standard only four decades ago.

Laugier and Hunziker pigmentation: a lentiginous proliferation of melanocytes.

Macular pigmentation of Laugier and Hunziker is an acquired disorder involving lips, oral mucosa, acral surfaces, nail apparatus, or a combination of these in the absence of systemic disease, and is reported to show intraepidermal melanosis without melanocytosis. We present a 69-year-old white man with typical features of this disorder, involving lips and oral mucosa, first appearing 4 years before presentation. A pigmented macule on sun-exposed lip vermilion revealed increased numbers of slightly atypical melanocytes in a lentiginous epidermal pattern.