Soluble tumor necrosis factor receptors are associated with severity of kidney dysfunction in pediatric chronic kidney disease.

Background: In adult chronic kidney disease (CKD) patients, there is a positive association between inflammation and progressive renal dysfunction. Higher levels of soluble receptors of tumor necrosis factor (sTNFR) have been related to worst prognosis of adult CKD patients. Therefore, the present study aimed to evaluate soluble TNF receptors in children and adolescents with CKD and to search for an association with clinical and laboratory features.

Anxiety, depression, resilience and quality of life in children and adolescents with pre-dialysis chronic kidney disease.

Background: Chronic kidney disease (CKD) is a risk factor for psychosocial impairment and psychiatric symptoms. Children and adolescents on dialysis frequently have compromised daily life activities and a worse quality of life (QoL) compared with healthy peers. However, few studies have investigated these aspects of CKD in pediatric pre-dialysis CKD patients.

Cognitive alterations in chronic kidney disease: an update.

Impairment of cognitive functions occurs frequently in chronic kidney disease (CKD). The conditions most associated with this decline are depression, delirium, mild cognitive impairment and dementia. The mechanisms involved have not been established yet, but some factors, as neuronal damage by uremic toxins, cerebrovascular ischemic lesions, oxidative stress, chronic inflammation, anemia, hyperhomocysteinemia, the endothelial dysfunction may play a critical role.

Behavioral characteristics of dysphonic children: integrative literature review.

Purpose: Integrative review of the scientific literature about the behavioral characteristics of dysphonic children discussing profiled and their etiologic relationship with the voice disorder, seeking to define recommendations on the importance of analyzing the behavior of children in voice assessment.

Research Strategy: Integrative review of articles published in the last 12 years, the Virtual Health Library.

Selection Criteria: Set up the theme of "behavioral characteristics of dysphonic children" was selected the databases LILACS, IBECS, MEDLINE, Cochrane Library, SciELO and ISI Web of Science and the following inclusion criteria: original articles, publication year from 2000 and 2012, Portuguese, English and Spanish.

Burning mouth syndrome: a therapeutic approach involving mechanical salivary stimulation.

Objective: The study aimed to evaluate the effects of salivary stimulation therapy on the salivary flow, quality of saliva, and symptoms in patients with burning mouth syndrome (BMS).

Background: BMS is a chronic disorder characterized by a burning sensation. Some reports have proposed a role for saliva in the pathogenesis of BMS.

The impact of burning mouth syndrome on health-related quality of life.

Background: Burning mouth syndrome is a chronic disorder that is characterized by a burning sensation and a normal clinical appearance of the oral mucosa. This condition often affects the health-related quality of life in patients. As such, the aim of this study was to compare the health-related quality of life of patients with BMS and healthy controls, using the validated Portuguese versions of the SF-36 and OHIP-49 questionnaires.