Publications by authors named "Arthur M C Kwan"
Background: Current ways to diagnose citrate accumulation (CA) in patients receiving regional citrate anticoagulation (RCA) continuous renal replacement therapy (CRRT) are confounded by various clinical factors. Serum citrate measurement emerges as a more direct way to diagnose CA, but its clinical utility and optimal cut-off values remain undefined. This study examined serum citrate kinetics and its diagnostic performance for CA in patients receiving RCA CRRT.
View Article and Find Full Text PDFBackground: The impact of neuraminidase inhibitors (NAIs) on influenza-related pneumonia (IRP) is not established. Our objective was to investigate the association between NAI treatment and IRP incidence and outcomes in patients hospitalised with A(H1N1)pdm09 virus infection.
Methods: A worldwide meta-analysis of individual participant data from 20 634 hospitalised patients with laboratory-confirmed A(H1N1)pdm09 (n = 20 021) or clinically diagnosed (n = 613) 'pandemic influenza'.
Effectiveness of neuraminidase inhibitors in reducing mortality in patients admitted to hospital with influenza A H1N1pdm09 virus infection: a meta-analysis of individual participant data.
Lancet Respir Med
May 2014
Article Synopsis
- The study analyzed the effectiveness of neuraminidase inhibitors in reducing mortality among hospitalized patients with the H1N1 virus during the pandemic.
- Data from 29,234 patients across 78 studies was examined to assess the impact of these antiviral treatments.
- Results showed that neuraminidase inhibitors reduced mortality risk, particularly when administered early (within two days of symptom onset), highlighting the importance of prompt treatment.