are known as higher producers of secondary metabolites with antimicrobial properties and plant growth promoters, including resistance induction. These mechanisms should be an alternative to pesticide use in crop production. causes Asian soybean rust, representing a high loss of yield around the world.
View Article and Find Full Text PDFOral squamous cell carcinoma (OSCC) is a worldwide public health problem, with high morbidity and mortality rates. The development of new drugs to treat OSCC is paramount. plant species have shown many biological activities.
View Article and Find Full Text PDFPharmaceutics
September 2021
is widely found in the Brazilian Cerrado, and commonly used in Brazilian folk medicine. In this study, we evaluated the effects of prolonged administration of the aqueous extract from leaves (AERV) on impaired redox status, renal dysfunction, and cardiovascular damage in 2K1C hypertensive rats, as well as its chemical composition by LC-DAD-MS. Renal hypertension (two kidney, one-clip model) was surgically induced in male Wistar rats and AERV (30, 100 and 300 mg/kg) was administered orally five weeks after surgery for 28 days.
View Article and Find Full Text PDFInformation on the knowledge, uses, and abundance of natural resources in local communities can provide insight on conservation status and conservation strategies in these locations. The aim of this research was to evaluate the uses, knowledge and conservation status of plants in two Quilombolas (descendants of slaves of African origin) communities in the Atlantic rainforest of Brazil, São Sebastião da Boa Vista (SSBV) and São Bento (SB). We used a combination of ethnobotanical and ecological survey methods to ask: 1) What ethnobotanical knowledge do the communities hold? 2) What native species are most valuable to them? 3) What is the conservation status of the native species used? Thirteen local experts described the names and uses of 212 species in SSBV (105 native species) and 221 in SB (96 native species).
View Article and Find Full Text PDFThe Aedes aegypti mosquito is one of the major vectors of arboviruses. These diseases have re-emerged and the insecticides used nowadays are toxic to mammals and environment and have only been effective in the short-term. In this context, natural products are an alternative.
View Article and Find Full Text PDFBackground: The genus Piper L. has the shikimic acid pathway predominantly expressed, biosynthesizing many cinnamic acid derivatives (CAD).
Objective: Neolignans comprise an important class of CAD that exhibit a wide range of pharmacological properties such as antibacterial, antitumor, insecticidal, anti-inflammatory, antioxidant, smooth muscle relaxant, neuroprotective, antiprotozoal and against platelet aggregation factor.