Exploring mono and bis-gold-DTC complexes against cancer and leishmania.

Cancer is one of the main challenges of global public health and a leading cause of death, hindering the increase in life expectancy, and Leishmaniasis occupies the second position in the number of deaths from parasitic diseases. Gold(I)-based drugs are being studied for chemotherapy and have been shown promising results, leading to the search for analogs with more favorable effect profiles. This work presents the synthesis and characterization of five new gold(I) complexes, [AuIDTCPPh3] and [AuI2DTC(PPh3)2], using dithiocarbamate-derived ligands and triphenylphosphine, with potential biological activity.