Publications by authors named "Arthur Henrique R Porto"
Immunol Lett
December 2017
Article Synopsis
- CD4+ and CD8+ T cells can be divided into different types based on surface markers, and these cells play a crucial role in the immune response to tuberculosis (TB), especially regarding their memory and effector functions.
- Patients with active pulmonary TB show a high proportion of IFN-ɣ+ and TNF-α+ central memory CD4+ T cells, indicating a potential protective response, while having fewer CD8+ T effector lymphocytes, which may lead to a weaker response against the bacteria.
- In contrast, those who have been treated for TB and individuals with latent infections exhibit a stronger response from memory CD4+ and CD8+ T cells, emphasizing the importance of long
