Publications by Arthur C S van den Burg

Publications by authors named "Arthur C S van den Burg"

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Coronavirus hemagglutinin-esterase and spike proteins coevolve for functional balance and optimal virion avidity.

Yifei Lang Wentao Li Zeshi Li Danielle Koerhuis Arthur C S van den Burg

Proc Natl Acad Sci U S A

October 2020

Human coronaviruses OC43 and HKU1 are respiratory pathogens of zoonotic origin that have gained worldwide distribution. OC43 apparently emerged from a bovine coronavirus (BCoV) spillover. All three viruses attach to 9--acetylated sialoglycans via spike protein S with hemagglutinin-esterase (HE) acting as a receptor-destroying enzyme.

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