Usefulness of collagen type IV in the detection of significant liver fibrosis in nonalcoholic fatty liver disease.

Introduction/aims: Liver fibrosis assessment is a key issue in the evaluation of nonalcoholic fatty liver disease (NAFLD) patients. In the present study, we aimed to validate a noninvasive marker panel to assess significant and advanced fibrosis in these patients.

Method: 126 biopsy-proven NAFLD patients were included.