Atypical Cogan's syndrome presenting as bilateral endogenous endophthalmitis.

We report a case of atypical Cogan's syndrome presenting as bilateral endogenous endophthalmitis in a woman with ovarian cancer. A 62-year-old woman with ovarian cancer developed bilateral interstitial keratitis and panuveitis accompanied by bilateral sensorineural hearing loss and chondritis. Auricular cartilage biopsy ruled out relapsing polychondritis and the diagnosis of atypical Cogan's syndrome was set clinically.

Diplopia due to systemic lupus erythematosus in a child: a rare clinical presenting sign of the disease.

We present the case of a 14-year-old girl who was admitted to the hospital with the complaint of horizontal diplopia for 48 hours. Initially, she was diagnosed with idiopathic intracranial hypertension. During hospitalization she developed fever, macular facial rash, and chest pain, and because of abnormal laboratory findings the diagnosis of systemic lupus erythematosus was established.

Decreased contrast sensitivity in children and adolescents with type 1 diabetes mellitus.

Purpose: To evaluate contrast sensitivity in children and adolescents with diabetes mellitus without evidence of diabetic retinopathy.

Methods: Sixty patients with insulin-dependent diabetes mellitus (age range: 8 to 18 years) were studied. Their contrast sensitivity scores were obtained using the CSV-1000 device (Vector Vision, Dayton, OH) for four spatial frequencies and were compared with v scores of 45 age-matched and gender-matched "healthy" patients.

Unusual case of acanthamoeba keratitis in a contact lens wearer.

Purpose: To present an atypical case of acanthamoeba keratitis in a soft contact lens wearer.

Methods: A case report of a 28-year-old female soft contact lens wearer with a 6-day history of redness and blurred vision in her right eye. Examination showed stromal keratitis that did not respond to therapy for herpes simplex virus.