Necrotizing fasciitis in a pediatric patient: Successful management in the inguinal area - A case report.

Introduction: Necrotizing fasciitis (NF) is a rare life-threatening medical and surgical emergency. We present a case of a pediatric patient diagnosed with necrotizing fasciitis in the inguinal area which required debridement and post-operative management of the residual wound using a combination of wound closure techniques.

Case Presentation: A 10-months-old girl with a history of Food-protein induced enterocolitis syndrome (FPIES) presented with septic shock and ulcerative lesions of the inguinal area.

Behavioral sexual dimorphism in models of anxiety and depression due to changes in HPA axis activity.

Anxiety and depression are considered as stress-related disorders, which present considerable sex differentiation. In animal models of anxiety and depression sex differences have been described and linked to the sexually dimorphic hypothalamus-pituitary-adrenals (HPA) axis. The present study aimed to adjust corticosterone, the main HPA axis stress hormone, in male and female adrenalectomized rats with oral (25 μg/ml) corticosterone replacement (ADXR).