Publications by authors named "Artem U Elmuratov"

Many cardiovascular diseases originate from growth retardation, inflammation, and malnutrition during early postnatal development. The nature of this phenomenon is not completely understood. Here we aimed to verify the hypothesis that systemic inflammation triggered by neonatal lactose intolerance (NLI) may exert long-term pathologic effects on cardiac developmental programs and cardiomyocyte transcriptome regulation.

View Article and Find Full Text PDF
Article Synopsis
  • Schizophrenia's molecular mechanisms remain unclear despite extensive studies in proteomics, metabolomics, and genome-wide associations; combining these advanced data can improve understanding of its pathogenesis.
  • In this study, researchers identified 20 proteins, many of which are new to schizophrenia, and 18 metabolite compounds linking to steroid and tyrosine transformations, underscoring their role in the disorder.
  • The integration of proteomic, metabolomic, and genomic data highlighted key factors like lipid transport, oxidative stress, and hormonal imbalances as crucial interconnected elements influencing schizophrenia pathology.
View Article and Find Full Text PDF

Temperature is an important exogenous factor capable of leading to irreversible processes in the vital activity of cells. However, the long-term effects of heat shock (HS) on mesenchymal stromal cells (MSC) remain unstudied. We investigated the karyotype and DNA repair drivers and pathways in the human endometrium MSC (eMSC) survived progeny at passage 6 after sublethal heat stress (sublethal heat stress survived progeny (SHS-SP)).

View Article and Find Full Text PDF