[Autoantibodies against lipoprotein(a) in patients with coronary heart disease].

Objective: Lipoprotein(a) - Lp(a) is an independent risk factor of atherosclerosis and its complications. In spite of the long period of Lp(a) research there is no complete understanding of its physiological role and atherogenic action. The goal of this study was to investigate the presence in human plasma of circulating autoantibodies to Lp(a) belonging to different classes of immunoglobulins, and to elucidate their relationship to the presence and severity of coronary atherosclerosis in middle aged patients with coronary heart disease.

[Effect of cascade plasma filtration on spectrum of subfractions of low density lipoproteins in blood plasma of patients with ischemic heart disease].

We studied effect of cascade plasma filtration on subfractions of low density lipoproteins (LDL) in 16 patients with ischemic heart disease (IHD) and hyperlipidemias refractory to drug therapy. The procedure caused 37.6 ± 1.

[Treatment of bile ducts injuries after laparoscopic cholecystectomy].

Features of bile ducts injuries after laparoscopic cholecystectomy were analyzed at 54 patients. High level of lesions (H. Bismuth III-IV type) was revealed at 80% cases.

[Effect of promethazine hydrochloride (pipolphen) on the stability of R plasmid resistance in Escherichia coli].

The influence of promethazin hydrochloride (pipolphen) on stability of R plasmid inheritance in Escherichia coli strains of various serogroups was studied. The strains were isolated from patients with acute intestinal infection and from healthy persons. It was shown that in subbacteriostatic concentrations (100 to 450 micrograms/ml) pipolphen promoted elimination of the R plasmids.

[Complications after endoscopic interventions on the major duodenal papilla].

An analysis of 83 cases of complications following endoscopic procedures on the major duodenal papilla was made: 62 cases after 2110 retrograde cholangiopancreatographies (RChPG) and 21 after 620 endoscopic papillosphincterotomies (EPST). Among most frequent complications there were acute pancreatitis (49 cases), purulent cholangitis (11 cases), suppurations of the pancreatic cysts and purulent pancreatitis (8 cases). Bleedings took place after EPST in 11 patients.

[Pancreatic juice peptides as possible regulators of reparative processes in the pancreas in acute and chronic pancreatitis].

The experiments were performed on 34 dogs. The subcutaneous injection of boiled pancreatic juice was established to increase the survival of dogs in acute destructive pancreatitis (p < 0.001) and to decrease the specific volume damage to acinar (p < 0.

[The importance of endoscopic papillosphincterotomy in biliary tract surgery].

Based upon 129 endoscopic operations in 98 patients with choledocholithiasis and stenosis of the major duodenal papilla the authors came to a conclusion on an increasing significance of endoscopic papillosphincterotomy (EPST) in the surgery of bile ducts. EPST was shown to be followed by less amount of complications and less lethality as compared with surgical papillosphincterotomy. The intrahospital lethality after EPST was 1%.

[Surgical treatment of congenital cysts of the common bile duct].

The article makes an analysis of the surgical tactics used in 9 patients with congenital cysts of the choledochus. In 3 patients the cysts were removed, in 1 patient internal drainage of the cyst was performed, in 4 patients the cysts were excised and hepato-jejunal or hepatocholedochoduodenal anastomoses were formed. There were no lethal outcomes after the operation.

[Replantation of the major duodenal papilla].

The authors describe 3 observations of replantation of the major duodenal papilla after its dissection from the duodenum. The results were favorable. There were no chronic pancreatitis or cholangitis.

[Chronic pancreatitis and cancer of the pancreas].

A microscopic study of 93 preparations of the pancreas from patients with a primary chronic pancreatitis allowed the authors to conclude that the primary chronic pancreatitis is a background favourable for the development of carcinoma, carcinoma of the pancreas being practically always accompanied by an acute inflammatory process. The presence of pancreatitis in patients with carcinoma of the pancreas is responsible for incompetence of pancreatoenteroanastomosis frequently developing in the postoperative period. The application of external controlled trans-anastomosis drainage of the common bile duct and pancreatic ducts resulted in more than 3 times less incidence of this complication.

[Surgical treatment of primary chronic pancreatitis].

Surgical methods of treatment of chronic alcoholic pancreatitis must be chosen with special reference to the state of the duct and parenchyma of the pancreas. Treatment of alcoholic patients should be performed with the participation of psychiatrists.

[Radiation exposure of the patient and personnel during punctures controlled by roentgenotelevision and computed tomography].

Determined by means of thermoluminescent dosimetry radiation exposure to a patient from punctures controlled by two-projection x-ray and TV was, on an average, 0.0176 Gy +/- 18%, and when controlled by CT it was 0.048 Gy +/- 22% which was comparable with dose exposure of 2 x-ray films in the first case and of 5 x-ray films in the second case.

[Causes of fatal outcomes in acute pancreatitis].

An analysis of case histories of 142 patients dead from acute pancreatitis has been made. The most frequent cause of death at early terms was the syndrome of endogenous intoxication and bleeding from upper portions of the gastro-intestinal tract. Death at later terms was usually caused by pyo-septic complications and arrosive bleedings.

[Reasons for relaparotomies following operations on the biliary tract in nontumorous lesions].

According to the authors' data the incidence of relaparotomies after 1500 operations for non-tumor diseases of bile ducts was 2.5%. Causes of relaparotomies at early and late terms of the postoperative period were different.

[Disorders of the coagulation, fibrinolytic and kallikrein-kinin systems of the blood in mechanical jaundice].

A clinico-experimental investigation of the state of the coagulating, fibrinolytic and Kallikrein-Kinin systems of blood in the mechanical jaundice syndrome and different methods of its operative treatment has shown activation of these systems. In jaundice resulting from tumor of the pancreas head and Vater papilla activation of the coagulating system was prevailing while activation of the fibrinolytic and Kallikrein-Kinin systems prevailed in non-tumorous jaundice. The operative treatment aimed at the recovery of choledynamics resulted in normalization of the coagulating, fibrinolytic and Kallikrein-Kinin systems.