Point Mutations in Furazolidone and Rifampicin Resistance Genes in Strains from Colombia.

The eradication of is a valid strategy for preventing gastric cancer; however, the therapeutic failure of first-line treatments in Colombia is associated with high resistance to metronidazole and amoxicillin. This study explored alternative antibiotics and analyzed point mutations in resistance genes to furazolidone and rifampicin in order to include them in rescue therapy regimens. A total of 239 complete genomes of Colombian strains were compared to that of the ATCC 26695 strain to identify mutations in the and genes for rifampicin and furazolidinone resistance, respectively.

Global and genetic diversity of SARS-CoV-2 in wastewater.

The analysis of SARS-CoV-2 in wastewater has enabled us to better understand the spread and evolution of the virus worldwide. To deepen our understanding of its epidemiological and genomic characteristics, we analyzed 10,147 SARS-CoV-2 sequences from 5 continents and 21 countries that were deposited in the GISAID database up until January 31, 2023. Our results revealed over 100 independent lineages of the virus circulating in water samples from March 2020 to January 2023, including variants of interest and concern.

Mathematical modelling of MS2 virus inactivation by Al/Fe-PILC-activated catalytic wet peroxide oxidation (CWPO).

Catalytic wet peroxide oxidation (CWPO) is a novel, alternative technology to conventional disinfection methods that are widely used to control microbial parameters in drinking water. To assess its effectiveness, new studies revealing the kinetics of MS2 coliphage inactivation by CWPO technology are required. This investigation therefore aimed to perform mathematical modelling of MS2 inactivation through CWPO technology activated by an Al/Fe-pillared clay catalyst (Al/Fe-PILC) in the presence of a synthetic surrogate of dissolved natural organic matter.

CWPO Degradation of Methyl Orange at Circumneutral pH: Multi-Response Statistical Optimization, Main Intermediates and by-Products.

The catalytic wet peroxide oxidation (CWPO) of the industrial azo-dye methyl orange (MO) activated by an Al/Fe-pillared clay catalyst was optimized by the Response-Surface Methodology (RSM). Three sequential sets of factorial 2 central composite experiments were required for the full optimization of the process; catalyst loading and stoichiometric dose of hydrogen peroxide were the experimental factors studied through different times of reaction by means of all, Dissolved Organic Carbon (DOC) removal, Total Nitrogen (TN) removal, reacted fraction of hydrogen peroxide, and decolorization as experimental responses to be maximized. The resulting single-response RSM optimums were combined in a multi-response Desirability function ruling out the differential effect of adsorption on the catalyst's surface by defining all responses per gram of clay catalyst.