Publications by authors named "Arsen Arsenievich Hudyma"
Article Synopsis
- The study investigated the differentiation and survival of human neural stem/progenitor cells (NSCs) from different origins when transplanted into injured spinal cords of rats.
- It was found that while neurospheres from HUES6 and iPSC lines showed potential for glial differentiation, they didn't fully mature into astrocytes in vitro but adapted to the spinal cord environment upon transplantation.
- Differences in survival and differentiation between the HUES6#1 and iPSC#1 neurospheres were linked to variations in signaling molecules related to their origins, with HUES6-derived cells producing a higher percentage of GFAP+ astrocytes compared to iPSC-derived ones in vivo.
