A significantly non-toxic novel Cobalt(III) Schiff base complex induces apoptosis via G2-M cell cycle arrest in human breast cancer cell line MCF-7.

Aims: Metal complexes have ignited considerable interest in the field of chemotherapy after the serendipitous discovery of cisplatin but the severe toxicity of these platinum-based drugs compelled researchers to search for newer, more effective lesser toxic anticancer drugs.

Materials And Methods: Structural analysis is done by different physicochemical techniques including X-ray single crystallography. Toxicity study has been done in normal Swiss albino mice.

Toward an integrated health data display for aging in place.

In a typical aging-in-place setting, electronic medical record, telemedicine data, and sensor data are used by different groups of decision makers, but the data may not be viewed in a holistic display to promote clinical decision making. Employing a user-centered design and evaluation framework, we analyzed relational data displays of congestive heart failure and provided an in-depth description of user characteristics, preferences, systems functionality, basic tasks and effective representations in such an information distributed setting. As a result, the prototypical design demonstrates our effort toward an integrated data display for chronic disease management in long-term care and clinical decision support which would enhance aging in place.