Publications by authors named "Arpana Sood"
Article Synopsis
- Long-term infection with Helicobacter pylori can lead to stomach cancer, but how the bacteria survive in the stomach is not well understood.
- A small RNA called HPnc4160 helps H. pylori adapt and produce proteins that may cause cancer.
- In experiments, bacteria without HPnc4160 were better at surviving in the stomach, and lower levels of this RNA were found in cancer patients compared to non-cancer patients.
Helicobacter pylori, a pathogenic bacterium that colonizes in the human stomach, harbors DNA repair genes to counter the gastric environment during chronic infection. In addition, H. pylori adapts to the host environment by undergoing antigenic phase variation caused by genomic mutations.
View Article and Find Full Text PDFPseudomonas aeruginosa-Candida albicans interactions: localization and fungal toxicity of a phenazine derivative.
Appl Environ Microbiol
January 2009
Phenazines are redox-active small molecules that play significant roles in the interactions between pseudomonads and diverse eukaryotes, including fungi. When Pseudomonas aeruginosa and Candida albicans were cocultured on solid medium, a red pigmentation developed that was dependent on P. aeruginosa phenazine biosynthetic genes.
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