Study of neoadjuvant chemotherapy in advanced malignant ovarian germ cell tumors at a tertiary center in western India.

Objective: To study clinical characters and outcomes in patients of malignant ovarian germ cell tumor (MOGCT) undergoing surgery following neoadjuvant chemotherapy (NACT).

Methods: Retrospective study of patients undergoing surgery following NACT for MOGCT at our institute. Platinum based chemotherapy was given in all patients in NACT.

A Scanning Electron Microscopic Study on Effect of Blood and Artificial Salivary Contamination on Marginal Adaptation of Mineral Trioxide Aggregate, When Used as a Retrograde Filling Material: An Study.

Aim And Objective: The present study was conducted to evaluate the marginal adaptability of mineral trioxide aggregate (MTA) as a root-end filling material when manipulated using two different IV fluids intended for pediatric usage; in the presence of blood and salivary contamination.

Materials And Methods: Sixty single-rooted teeth were selected. Conventional endodontic root canal preparation was performed on all specimens followed by root-end resection and retrograde cavity preparation.

Female genital tract melanoma: Analysis from a regional cancer institute.

Objective: Malignant melanoma of the genital tract comprises 3% of all melanomas afflicting females. They are characterized by poor prognosis with 5-year survival of 0-25% and high incidence for distant metastasis. This study was performed to assess various clinical features, treatment options, and thre management of genital melanomas.

Prognostic value of lymph node ratio in surgically treated cases of vulvar cancer: a tertiary care centre experience.

Objective: This study aimed to study the patterns of recurrence in surgically treated cases of vulvar cancer (VC) and determine the factors associated with recurrence, with a special emphasis on lymph node ratio (LNR).

Methods: This retrospective study examined VC patients primarily treated with surgery at our institute from January 2005 to December 2015. Demographic data, clinical characteristics, surgicohistopathological data, adjuvant treatment, follow up, and recurrence site and treatment were studied.

Does preoperative CA-125 cutoff value and percent reduction in CA-125 levels correlate with surgical and survival outcome after neoadjuvant chemotherapy in patients with advanced-stage ovarian cancer? - Our experience from a tertiary cancer institute.

Aim: The aim of the study is to evaluate percent fall in CA-125 levels after neoadjuvant chemotherapy (NAC) and preoperative CA-125 value to predict surgical and survival outcomes in women with advanced-stage epithelial ovarian cancer (EOC).

Methods: A retrospective review of 406 women receiving NAC for advanced-stage EOC from January 2012 to July 2015 was conducted. Data were collected for demography, radiographic profile, CA-125 levels before and after NAC, chemotherapy, and surgicopathological information.

Caries risk in children of Udaipur City, India using genetic taste sensitivity to 6--propylthiouracil.

Aims And Objectives: Dental caries still remains the single most common disease of childhood. The present study was conducted to test the hypothesis that a higher prevalence of dental caries would be observed among nontaster children compared to medium tasters or supertasters of 6n propylthiouracil impregnated filter papers.

Materials And Methods: The present study was conducted on a random sample of 600 school children aged 6-12 years in Udaipur city.

Antibacterial Activity of Two Chemomechanical Caries Removal Gels on Carious Dentin of Primary Teeth: An in vitro Study.

Introduction: Chemomechanical caries removal (CMCR) is an effective method of caries removal especially for primary teeth as they cause less discomfort when compared with conventional caries removal. The most significant thing about caries removal is the elimination of cariogenic bacteria. This study compares the antibacterial activity of two CMCR gels.

Ovarian Fibroma: A Clinico-pathological Study of 23 Cases with Review of Literature.

Purpose: The purpose of this study was to correlate the clinical findings, RMI-4 index and frozen section, in cases of ovarian fibroma with the final histopathology.

Methods: This is a retrospective study of clinical and pathological features of 23 patients of ovarian fibroma. The patient's age ranged from 34 to 66 years (mean-49 years).

Postendodontic restoration of severely decayed primary tooth using modified omega loop as a post.

The esthetic concern of severely mutilated primary anterior teeth in the case of early childhood caries has been a challenge to pediatric dentist. Early childhood caries is the most common chronic disease of the preschool child. The case report presented here is of a three year old boy with severely decayed maxillary anterior teeth.

Assessment of microbial contamination on twice a day used toothbrush head after 1-month and 3 months: An in vitro study.

Purpose: The purpose of vitro study was to assessment of the bacterial contamination on daily twice-used toothbrushes in different conditions after 1-month and 3 months.

Materials And Methods: Forty children aged between 6 and 12 years were selected for this study. Toothbrushes and toothpaste were distributed among those children.

Maternal Dental Anxiety and its Effect on Caries Experience Among Children in Udaipur, India.

Context: Dental caries is a common oral disease among children. There are various factors that influence caries development. Parents and family environment influence oral health behaviours among children.

Comparison of relationship between salivary electrolyte levels and dental caries in children with Down syndrome.

Aim: The aim of this study was to relate the salivary electrolyte levels with dental caries in children with Down syndrome and to compare salivary electrolyte levels and dental caries of these children with their siblings.

Materials And Methods: Study population consisted of 30 Down syndrome children (study group) and their 30 healthy siblings (control group). Caries status was determined by dental caries indices in deciduous and permanent dentitions.

Role of cone beam computed tomography and white mineral trioxide aggregate in the successful management of a permanent anterior tooth with open apex.

Cone beam computed tomography (CBCT) is a recent three-dimensional (3D) radiographic imaging modality used for the accurate diagnosis, management and follow-up of endodontic problems. In tooth with open apex and periapical lesion, the use of new obturation material such as white mineral trioxide aggregate (wMTA) facilitates faster and more predictable closure of root apex and periapical healing. The objective of this case report was to evaluate the role of CBCT and wMTA obturation in management of a permanent anterior tooth with open apex and periapical lesion.

Comparative evaluation of microleakage of three restorative glass ionomer cements: An in vitro study.

Purpose: The aim of this study was to compare the microleakage of glass ionomers (conventional and resin modified) with that of recently introduced nanoionomers.

Materials And Methods: Standardized class I and class V cavities were prepared on 120 young permanent teeth. Samples were equally divided into group I (class I restorations) and group II (class V restorations), and further divided into subgroups.

Rehabilitation of complicated crown-root fracture by fragment reattachment and intraradicular splinting: case reports.

This paper describes the rehabilitation of two traumatised teeth in two patients namely; A maxillary left central incisor with a relatively rare combination of multiple fractures- uncomplicated crown fracture, complicated crown-root fracture along with an oblique fracture in middle third of the root and A traumatised mandibular central incisor with a horizontal fracture in cervical third of the root and complete separation of the fragments. In both cases, initially the fractured crown fragments were extracted which was followed by pulpectomy and placement of fiber posts luted with resin cement. The fractured fragments were then reattached to the respective teeth using resin cement.

Evaluation of physio-chemical properties of saliva and comparison of its relation with dental caries.

Objective: Objective was to evaluate the relationship between physio-chemical properties of saliva such as flow rate, buffering capacity, pH, Streptococcus mutans in saliva and its relationship with dental caries.

Study Design: Eighty children were evaluated for physio-chemical properties of saliva, out which 40 were caries-active (group 1) and 40 caries-free (control group). Caries status of each child was scored by using DMFS and dfs indices to get a combined DMFS and dfs score.

Comparative evaluation of the antibacterial effects of four dentine bonding systems: An in vitro study.

Aim: The aim of this in vitro study was to evaluate and the compare antibacterial efficacy of four dentin bonding system against Streptococcus mutans, Streptococcus salivarius and Lactobacillus acidophilus over a period of three months using agar disk diffusion test.

Methodology: All the three standard bacterial strains were inoculated into BHI broth and incubated at 37°C for 48 hours. A 100 μl of broth suspension containing aliquots of S.

Neurological features of epilepsy, ataxia, sensorineural deafness, tubulopathy syndrome.

Aim: Recently, we reported a previously unrecognized symptom constellation comprising epilepsy, ataxia, sensorineural deafness, and tubulopathy (EAST syndrome) associated with recessive mutations in the KCNJ10 gene. Here, we provide a detailed characterization of the clinical features of the syndrome to aid patient management with respect to diagnosis, prognostic counselling, and identification of best treatment modalities.

Method: We conducted a retrospective review of the detailed neurological and neuroradiological features of nine children (four females, five males; age range at last examination 6-20y) with genetically proven EAST syndrome.

Granulosa cell tumours: a study of 37 cases.

Objectives: To evaluate the clinico-pathological features, surgical procedures and postoperative treatment and their relation to survival in women with granulosa cell tumours.

Methods: Data of 37 women with granulosa cell tumours were collected and reviewed retrospectively. Mann-Whitney test, log rank test and Kaplan-Meier survival analysis were applied appropriately.

Clinical evaluation of the plaque-removing ability of four different toothbrushes in visually impaired children.

Purpose: To evaluate the efficacy of plaque removal of four different toothbrushes in visually disabled children. Three manual toothbrushes with different bristle designs (Oral-B CrossAction 40-regular, Oral-B ShinyClean 40-soft, Oral-B Advantage 40-soft) were compared with an electric toothbrush with an oscillating rotating head (Colgate Motion).

Materials And Methods: Forty visually impaired children in a professional education center participated in the study and were divided into 4 groups of 10 participants each.