Publications by authors named "Arni Saemundsson"
Article Synopsis
- - Bronchial squamous carcinoma in situ (CIS) is a precursor to invasive carcinoma, and a study from 1992 to 2016 examined its prevalence, molecular markers, and outcomes among affected individuals.
- - Out of 31 CIS cases, 22 were found alongside invasive carcinomas, with some invasive tumors being undetectable through imaging; CIS can sometimes spread to other lung areas or transform into invasive cancer.
- - Although isolated CIS can regress, it often accompanies invasive tumors, and genetic findings, such as TP53 mutations and chromosomal changes, may help understand the progression of these lesions in the airways.
Background: The study aimed to validate the prognostic value of the Prostatype® risk score (P-score), which includes a three-gene signature and conventional risk factors, in a retrospective cohort.
Methods: All 716 patients diagnosed with prostate cancer from 2008 to 2010 at Skåne University Hospital, Sweden, were included. After excluding patients based on pathological and clinical eligibility criteria, RNA quality, and presence of metastases at diagnosis, a final cohort comprising 316 patients was further analyzed.
Background: Since the introduction of pneumococcal conjugate vaccines, vaccine type pneumococcal carriage and disease has decreased world-wide. The aim was to monitor changes in the nasopharyngeal carriage of pneumococci, the distribution of serotypes and antimicrobial resistance in children before and after initiation of the 10-valent pneumococcal vaccination in 2011, in a previously unvaccinated population.
Methods: Repeated cross-sectional study at 15day-care centres in greater Reykjavik area.