Publications by Arne Hoerlyck

Publications by authors named "Arne Hoerlyck"

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Renal effects of long-term ciclosporin A treatment in a large animal model.

Donata Cibulskyte Anne Samsoe Engberg Daniel Hanefelt Kristensen Anne Ringer Ellingsen Michael Pedersen Arne Hoerlyck

Nephron Exp Nephrol

April 2007

Background: Most experimental studies of chronic ciclosporin A (CsA) nephrotoxicity have been performed in rodents; however, the pig possesses several advantages. The aim of this study was to investigate renal functional and structural changes during CsA treatment with 20 mg/kg/day for 6 months in a pig model.

Methods: Gottingen minipigs were randomized to oral CsA treatment or as controls.

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