Frontal Bone Morphology in Different Age and Gender Groups Using Computed Tomography.

Background:  The shape of the forehead is primarily determined by the frontal bone, which holds significance for health and aesthetics. This study evaluated the morphology of the frontal bone in different age groups and genders using computed tomography (CT).

Methods:  This cross-sectional study was conducted on CT scan results of 220 patients divided into three age groups: 20-29.

Predicting overall survival in anaplastic thyroid cancer using machine learning approaches.

Purpose: Anaplastic thyroid carcinoma (ATC) is a highly aggressive and lethal thyroid cancer subtype with a poor prognosis. Recent advancements in machine learning (ML) have the potential to improve survival predictions. This study aimed to develop and validate ML models using the SEER database to predict 3-month, 6-month, and 12-month (overall survival) OS in ATC patients.

Thy-DAMP: deep artificial neural network model for prediction of thyroid cancer mortality.

Purpose: Despite the rising incidence of differentiated thyroid cancer (DTC), mortality rates have remained relatively low yet crucial for effective patient management. This study aims to develop a deep neural network capable of predicting mortality in patients with differentiated thyroid cancer.

Methods: Leveraging data from the Surveillance, Epidemiology, and End Results (SEER) database, we developed Thy-DAMP (Deep Artificial Neural Network Model for Prediction of Thyroid Cancer) to forecast mortality in DTC patients.

Donepezil in the treatment of ischemic stroke: Review and future perspective.

Ischemic stroke remains the leading cause of morbidity and the second most common cause of mortality worldwide. Over the past decade, endovascular thrombectomy (EVT) drastically changed the care of patients with ischemic stroke due to large vessel occlusion. Nevertheless, despite revascularization, many patients do not achieve a good functional outcome.

Poor Utilization of Nimodipine in Aneurysmal Subarachnoid Hemorrhage.

Objective: To determine adherence to nimodipine administration in patients admitted with aneurysmal subarachnoid hemorrhage (aSAH).

Background: Oral nimodipine (60 mg every 4 hours for 21 days) is recommended by the national guidelines for aSAH. A Cochrane systematic review has determined that nimodipine reduces the risk of cerebral ischemia and is currently the only effective drug for the prevention of vasospasm in aSAH patients.

Fingolimod exerts neuroprotective effects in a mouse model of intracerebral hemorrhage.

Recent studies have shown that fingolimod (FTY720) is neuroprotective in CNS injury models of cerebral ischemia and spinal cord injury. The purpose of the study was to examine the effect of fingolimod in a mouse model of intracerebral hemorrhage. ICH was produced in adult CD1 mice by injecting collagenase VII-S (0.