Publications by authors named "Arnaud Thierry Djami-Tchatchou"

Article Synopsis
  • Small antifungal peptides known as NCR peptides, particularly in legumes like chickpeas, show potential as biofungicides due to their ability to act against fungal pathogens through different mechanisms of action (MoA).
  • The study focused on chickpea NCR13, which can form multiple disulfide bonds; two variants of this peptide, NCR13_PFV1 and NCR13_PFV2, were created, showing different structures and antifungal potency despite having the same amino acid sequence.
  • NCR13_PFV1 was found to be more effective in killing fungal cells and inhibiting protein translation, resulting in better disease control in plants sprayed with it, emphasizing the importance of disulfide bond configuration in peptide
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White mold disease caused by a necrotrophic ascomycete pathogen results in serious economic losses of soybean yield in the USA. Lack of effective genetic resistance to this disease in soybean germplasm and increasing pathogen resistance to fungicides makes white mold difficult to manage. Small cysteine-rich antifungal peptides with multi-faceted modes of action possess potential for development as sustainable spray-on bio-fungicides.

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Chemical fungicides have been instrumental in protecting crops from fungal diseases. However, increasing fungal resistance to many of the single-site chemical fungicides calls for the development of new antifungal agents with novel modes of action (MoA). The sequence-divergent cysteine-rich antifungal defensins with multisite MoA are promising starting templates for design of novel peptide-based fungicides.

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The auxin indole-3-acetic acid (IAA) is a plant hormone that not only regulates plant growth and development but also plays important roles in plant-microbe interactions. We previously reported that IAA alters expression of several virulence-related genes in the plant pathogen Pseudomonas syringae pv. tomato strain DC3000 (DC3000).

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