Publications by authors named "Arnaldo Cioni"
Efficacy and Tolerability of Brevilin-A, a Natural JAK Inhibitor, in Pediatric Alopecia Areata: A Case Series.
Clin Cosmet Investig Dermatol
October 2024
Article Synopsis
- - Alopecia areata is an autoimmune disorder that damages hair follicles on the scalp and body, leading to hair loss.
- - Janus kinase inhibitors are effective in treating adults with this condition, while topical treatments like Brevilin-A have shown promise for children and adolescents with mild to moderate cases.
- - Brevilin-A, derived from Centipeda minima, works by blocking specific signaling pathways and has been successfully used in pediatric patients, indicating it could be a safe and effective option for challenging cases of alopecia areata in younger populations.
Tildrakizumab, an IL-23 inhibitor, is effective and safe for the improvement of moderate-to-severe chronic plaque psoriasis. However, little evidence is available on the use of this biologic in psoriasis in difficult-to-treat locations. In this retrospective analysis, we treated patients with 100 mg tildrakizumab at Day 0, after 4 weeks and every 12 weeks thereafter.
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