Publications by authors named "Armeta Dastyer"
Effect of sex steroid hormones on replication and transmission of major HIV subtypes.
J Steroid Biochem Mol Biol
November 2013
Article Synopsis
- The HIV epidemic is increasingly global, with women comprising half of all HIV-1 infections; understanding how sex hormones influence different HIV subtypes' pathogenesis is crucial.
- The study tested the effects of sex hormones on HIV replication and transmission using blood cells from male and female donors infected with various HIV subtypes; hormone levels impacted virus production but results varied by donor and subtype.
- Findings indicated that subtypes B and C replicated more efficiently in both genders’ blood cells and were transmitted more effectively, yet the role of sex hormones on entry receptors did not align with virus replication levels.