Publications by authors named "Armenio Coimbra Serra"
In this work, dextran-based nerve tube-guides were prepared, characterized and used in a standardized animal model of neurotmesis injury. Non-porous and porous transparent tube-guides were obtained by photocrosslinking of two co-macromonomers based on dextran and poly(ε-caprolactone) (PCL). Swelling capacity of the tube-guides ranged from 40-60% with no visible constriction of their inner diameter.
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- The study introduces a new nonionic porphyrin called ACS769F4, which shows enhanced bactericidal effectiveness against E. coli and Staphylococcus aureus with fewer side effects on mammalian cells.
- Unlike the existing photosensitizer TTAP(4+), ACS769F4 does not negatively affect human embryonic or hamster kidney cells, preserving their viability and cellular structure.
- Its low toxicity and strong antibacterial properties make ACS769F4 a promising candidate for clinical applications in bacterial photodynamic inactivation.