Antimicrobial Activity of Melanin Isolated from Wine Waste.

Melanins have immense application potential in the fields of agriculture, cosmetics and pharmaceutical industries. To determine the antimicrobial properties of melanin, conditionally pathogenic bacteria, belonging to different taxonomic groups were used. The results have shown that melanin solution exhibited bacteriostatic or bactericide activity depending on test culture and melanin concentration.

BartSmiles: Generative Masked Language Models for Molecular Representations.

We discover a robust self-supervised strategy tailored toward molecular representations for generative masked language models through a series of tailored, in-depth ablations. Using this pretraining strategy, we train BARTSmiles, a BART-like model with an order of magnitude more compute than previous self-supervised molecular representations. In-depth evaluations show that BARTSmiles consistently outperforms other self-supervised representations across classification, regression, and generation tasks, setting a new state-of-the-art on eight tasks.

Characteristic of Bacteriocins of Lactobacillus rhamnosus BTK 20-12 Potential Probiotic Strain.

Multidrug resistance (MDR) is a serious health threat throughout the world resulting in reduced efficacy of antibacterial, antiparasitic, antiviral, and antifungal drugs. One of the most promising concepts that may represent a good alternative to antibiotics can be the use of bacteriocins obtained from lactic acid bacteria. The L.

Isolation, purification and physicochemical characterization of water-soluble Bacillus thuringiensis melanin.

Melanins are widely used in medicine, pharmacology, cosmetics and other fields. Although several technologies for the purification of water-insoluble dioxyphenylalanine (DOPA) melanins have been described, a source of water-soluble melanin is highly desirable. Here we describe an effective procedure for the isolation and purification of water-soluble melanin using the culture medium of Bacillus thuringiensis subsp.