Publications by authors named "Armelle Junchat"
Front Microbiol
September 2024
Article Synopsis
- A study was conducted at Tours University Hospital to investigate an outbreak of linezolid-resistant strains of bacteria (LRSE) from 2017 to 2021, focusing on their resistance mechanisms and transmission routes.
- Out of 34 LRSE isolates, 20 were analyzed, revealing high resistance to linezolid linked to a specific genetic mutation, with most strains being closely genetically related (95% similarity).
- The findings suggest that prior use of linezolid may have contributed to the outbreak, and hand-to-hand transmission by healthcare workers could have played a role; the study also evaluated a new typing method, IR-Biotyper, which showed promise for future use.
