Blood Pressure Treatment Adherence and Control after Participation in the ReHOT.

Background:: Lack of adherence to pharmacological treatment is one of the main causes of low control rates in hypertension.

Objective:: To verify treatment adherence and associated factors, as well as blood pressure (BP) control in participants of the Resistant Hypertension Optimal Treatment (ReHOT) clinical trial.

Method:: Cross-sectional study including all 109 patients who had completed the ReHOT for at least 6 months.

Cardiovascular mortality among a cohort of hypertensive and normotensives in Rio de Janeiro - Brazil - 1991-2009.

Background: Although there is strong evidence of the benefits of antihypertensive treatment, the high prevalence of this important cardiovascular risk factor and its complications, as well as the low control rates of hypertension observed in many studies justify the investigation of these relationships in population studies. The objective was to investigate the ratio of cardiovascular disease mortality between hypertensives (non-treated, controlled and uncontrolled) and non-hypertensives in a cohort of a population sample of adults living in Ilha do Governador, Rio de Janeiro state, Brazil, who were classified in a survey conducted in 1991 and 1992 and whose death certificates were sought 19 years later.

Methods: A cohort study was performed on probabilistic linkage between data from an epidemiological study of hypertension performed in Ilha do Governador, in Rio de Janeiro, Brazil (1991 to 1992) and data from the Mortality Information System of Rio de Janeiro (1991 to 2009).

Resistant hypertension optimal treatment trial: a randomized controlled trial.

The prevalence of resistant hypertension (ReHy) is not well established. Furthermore, diuretics, angiotensin-converting enzyme inhibitors or angiotensin-receptor blockers, and calcium channel blockers are largely used as the first 3-drug combinations for treating ReHy. However, the fourth drug to be added to the triple regimen is still controversial and guided by empirical choices.

Ambulatory blood pressure monitoring and cardiovascular risk in resistant hypertensive women.

Background: Few studies have explored the prognostic value of ambulatory blood pressure (ABP) in resistant hypertensive patients, a high-risk group.

Objective: To investigate the prognostic value of uncontrolled daytime ABP in resistant hypertensive women.

Methods: We followed 382 resistant hypertensive women, aged 24-92 years, from a hypertension unit of a university hospital, for up to 8.

Office blood pressure and 24-hour ambulatory blood pressure measurements: high proportion of disagreement in resistant hypertension.

Objective: To evaluate the accuracy and quantify the agreement between office blood pressure (BP) and daytime ambulatory BP monitoring in the assessment of BP control of patients with a clinical diagnosis of resistant hypertension.

Study Design And Setting: Office BP measurements were done in a cohort of 228 true resistant (TR) or white-coat resistant (WCR) hypertensives classified by ambulatory BP in a hypertension clinic in Rio de Janeiro in this validity study. The agreement between the daytime ambulatory BP and office BP was analyzed using the graphic methods of Altman -- Bland and survival -- agreement plots.

Factors associated with microalbuminuria in resistant hypertension.

Microalbuminuria is a well-known marker for cardiovascular and renal complications. The purpose of our study was to identify factors associated with microalbuminuria in individuals with resistant hypertension. Urine albumin excretion (UAE) was evaluated in 187 patients with resistant hypertension.

True resistant hypertension: is it possible to be recognized in the office?

Background: True resistant hypertension (RH) is defined as uncontrolled office and ambulatory blood pressure (BP) in spite of an optimal regimen with at least three antihypertensive drugs. The aim of this study is to identify, in the office, clinical, laboratory, electrocardiographic, and echocardiographic variables associated with the occurrence of true RH.

Methods: These variables were recorded in a cross-sectional study involving 497 resistant hypertensive patients diagnosed by ambulatory BP monitoring as true RH (63.

Demographic and clinical characteristics of hypertensive patients in the internal medicine outpatient clinic of a university hospital in Rio de Janeiro.

Context: Hypertension is one of the most important cardiovascular risk factors but its control is still a challenge for physicians all around the world. For blood pressure control to be improved, it is important to guarantee the quality of attendance provided for hypertensive patients, especially in teaching hospitals, where future physicians are being trained.

Objective: To characterize the profile of hypertensive patients attending the internal medicine outpatient clinic of a university hospital in Rio de Janeiro,describing their cardiovascular risk and identifying flaws in the treatment provided for severely hypertensive patients, in order to implement an arterial hypertension management program.

Orlistat in hypertensive overweight/obese patients: results of a randomized clinical trial.

Objective: To assess the effect of orlistat plus diet compared with diet alone in promoting weight loss and blood pressure reduction in hypertensive, overweight/obese patients.

Design: A pragmatic randomized, controlled trial.

Setting: Hypertension clinic of a university hospital.

Socioeconomic aspects of spousal concordance for hypertension, obesity, and smoking in a community of Rio de Janeiro, Brazil.

Objective: The present study aims to evaluate the environmental role in the distribution of hypertension, obesity, and smoking and spousal concordance for the presence/absence of these 3 cardiovascular risk factors.

Methods: A cross-sectional study was conducted in a community in Rio de Janeiro, Brazil. The households were randomly selected.