Publications by authors named "Arlinda S Wahyuni"

Introduction: Plant treatment has been used for thousands of years and has been proven to treat acute and chronic diseases. The function of the traditional plant is as an antimicrobial agent, anticancer, antioxidant, and therapeutic gene in healing wounds and inflammation. Lung fibrosis caused by bleomycin can develop into chronic lung disease, which ends in tissue death if not treated immediately.

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  • COVID-19 continues to impact global health significantly, with its mechanisms not fully understood; key players in the virus's entry into cells are ACE2 and TMPRSS2, whose genetic variations have been studied for their impact on disease severity.
  • A study conducted in 2022 involving 151 hospitalized COVID-19 patients in Indonesia assessed the relationship between specific genetic polymorphisms (rs2074192 and rs12329760) and the outcomes of the disease, along with demographic data and health status.
  • Although the study found no strong links between the tested genetic variants and severe disease outcomes, it did note that the TMPRSS2 SNP was associated with higher mortality, and that ACE2 protein levels differed significantly between
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This study investigated indicators of the severity and mortality of COVID-19 in children in Medan, Sumatera Utara Province, Indonesia. The aim of this study was to identify determinants of severity and outcome of children with COVID-19 as the lesson learned from the COVID-19 pandemic, particularly the limited health facilities in Indonesia. This retrospective cohort study was conducted in 2020, 2021, and 2022 at multiple centers.

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Aims And Background: In postoperative patients in the intensive care units (ICUs), not only analgesics are needed but also sedation so that the patient can remain calm during treatment, especially patients with mechanical ventilation. By using the measurement parameters of the quantum consciousness index (qCON) and quantum noxious index (qNOX) in measuring the depth of sedation and adequacy of analgesics, the use of subdose ketamine instead of fentanyl and midazolam as sedative, analgesic agents can be performed as a new alternative to nociceptive monitoring methods with more objective results. This study aims to obtain results of comparing qCON and qNOX in postoperative patients by administering subdose ketamine compared with a combination of fentanyl and midazolam in RSUP Haji Adam Malik Medan.

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Prolonged physical and mental health changes, known as post-COVID conditions (PCC), could impair the quality-of-life (QoL) of healthcare workers. The aim of this study was to identify factors that contribute to cognitive impairments and QoL among COVID-19 survivors working as healthcare workers. This cross-sectional study involved healthcare workers at Prof.

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Chronic obstructive pulmonary disease (COPD) presents a significant global challenge, impacting health systems, economies, and societies. Its prevalence is anticipated to rise owing to an aging demographic. Although the PUMA and CAPTURE questionnaires are available for COPD screening, their comparative effectiveness has not been studied in Indonesia.

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  • Diabetic Peripheral Neuropathy (DPN) is a common complication in Type 2 Diabetes Mellitus, causing symptoms like pain and numbness in limbs; the Diabetic Neuropathy Symptom-Score (DNS) is an effective tool for detection.
  • A study analyzed 85 T2DM patients, finding that 85.9% had DPN, with significant associations between DPN and higher levels of cholesterol, HbA1c, Nitric Oxide (NO), and Vascular Endothelial Growth Factor (VEGF).
  • The study concludes DNS is useful for early screening of DPN, highlights the role of NO and VEGF in DPN progression, and suggests that education and exercise can help prevent
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Background: Many researchers have been indicated that premature hair greying (PHG) may be associated with the multifactorial problem include genetic, trace elements deficiencies and some medical problems such as metabolic disorders. However, the risk factors for premature hair greying are not well known for young adult.

Aim: This study aimed to determine the risk factors of hair greying in young adult.

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Background: Hypertension is one of the major health issues among senior citizens considering the increase in the population of a senior citizen's over the age of 60 in Indonesia. The use of antihypertensive drugs alone has proved to be inadequate to exhibit long-term effects of blood pressure control if it is not supported by adherence.

Aim: This study aims to investigate the relationship between knowledge, attitude, action, and doctor's communication to adherence of hypertensive patient in taking medication.

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Background: The prevalence of prehypertension in the world reaches 20-25% with a figure that is still high in Indonesia (48.4%). The role of health promotion is substantial in an effort of prevention and treatment of hypertension.

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Background: Diabetic neuropathy is one of the most complicated complications of diabetes patients with Type 2 diabetes.

Aim: The purpose of this study was to determine the diagnosis of diabetic neuropathy based on Clinical Neurological Examination (CNE) and the factors that influence the occurrence of diabetic neuropathy in Type 2 DM patients at Amplas Primary Health Care (PHC) in Medan City.

Methods: The research design was descriptive-analytic with the cross-sectional approach.

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Background: High incidence rate of diabetes mellitus (DM) and increased incidence of complications from DM as well as the use of less effective antidiabetic drugs and high financing to treat demands alternative therapy.

Aim: This study was conducted to determine the difference in the effect of Arabica coffee gayo bean and leaf extract on blood sugar levels in healthy mice before and after the intervention of extract and fasting and postprandial blood glucose level after consumption of glucose.

Methods: This research is an experimental research study.

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Background: Technology has provided a type of facility in the world that currently makes the world like a virtual globe. One of the technologies currently used by humans is gadgets. Generally, children and adolescents nowadays often use gadget excessively.

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Background: Asthma is a chronic airway disease that is based on an inflammatory process and a serious health problem around the world. Asthma is often associated with treatment management factor. Adherence is the patient's compliance towards their doctor's advice, which is accompanied by their understanding and follows the doctors' advice consistently.

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Background: Serum Procalcitonin (PCT) is a biomarker that is frequently used to diagnose an infection. In some cases of thoracic malignancy, procalcitonin level appears to increase. However, the role of procalcitonin to diagnose malignancy is not certain yet, and the causes have not been known.

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Aim: This study aimed to analyse tuberculosis (TB) medication-taking behaviour based on the concept of concordance between health workers and TB patients in Medan, Indonesia.

Methods: This study was an analytical study with a cross-sectional design. A total of 100 patients undergoing TB treatment at several public health centres in Medan City participated in the study.

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