Estimation of renal function immediately after cessation of continuous renal replacement therapy at the ICU.

Estimating glomerular filtration (eGFR) after Continuous Renal Replacement Therapy (CRRT) is important to guide drug dosing and to assess the need to re-initiate CRRT. Standard eGFR equations cannot be applied as these patients neither have steady-state serum creatinine concentration nor average muscle mass. In this study we evaluate the combination of dynamic renal function with CT-scan based correction for aberrant muscle mass to estimate renal function immediately after CRRT cessation.

Unlocking maintenance-architecting STEP for maintenance and realizing remountable magnet joints.

The architecture of the Spherical Tokamak for Energy Production (STEP) has been developed to enable a hybrid maintenance approach using ports in the vacuum vessel for a limited list of tasks that must be performed shortly after shutdown, and larger openings to simplify and speed up major refits. Robotic handling systems in zero-human entry facilities will prevent workers from being exposed to the most hazardous environments. While the approach is largely grounded in existing technologies, the scale and environment of STEP will require significant technology development.

Regional Impact of COVID-19-Associated Pulmonary Aspergillosis (CAPA) during the First Wave.

Background: Critically ill COVID-19 patients have proven to be at risk for developing invasive fungal infections. However, the incidence and impact of possible/probable COVID-19-associated pulmonary aspergillosis (CAPA) in severe COVID-19 patients varies between cohorts. We aimed to assess the incidence, risk factors, and clinical outcome of invasive pulmonary aspergillosis in a regional cohort of COVID-19 intensive care patients.

Feedback of ATP measurement as a tool for reducing environmental contamination in hospitals in the Dutch/Belgian border area.

Design: A two-phase prospective intervention study.

Objective: The objective of this study was to determine if feedback of adenosine triphosphate (ATP) measurements decreases environmental contamination within hospitals in the Dutch/Belgian border area.

Methods: Standardized ATP measurements were conducted in nine hospitals on pre-defined fomites.

Aspergillus Test Profiles and Mortality in Critically Ill COVID-19 Patients.

The literature regarding COVID-19-associated pulmonary aspergillosis (CAPA) has shown conflicting observations, including survival of CAPA patients not receiving antifungal therapy and discrepancy between CAPA diagnosis and autopsy findings. To gain insight into the pathophysiology of CAPA, we performed a case-control study in which we compared Aspergillus test profiles in CAPA patients and controls in relation to intensive care unit (ICU) mortality. This was a multinational case-control study in which Aspergillus test results, use of antifungal therapy, and mortality were collected from critically ill COVID-19 patients.

The correlation between ATP measurement and microbial contamination of inanimate surfaces.

Background: The objective of this study was to determine the correlation between adenosine triphosphate (ATP) measurements and microbial contamination using a standardized method. Secondarily, analyzing reproducibility of ATP measurements and aerobic colony counts (ACC's) on the same surface.

Methods: ATP measurements and ACC's were conducted on 10 pre-defined fomites in a hospital and nursing home setting.

ATP measurement as an objective method to measure environmental contamination in 9 hospitals in the Dutch/Belgian border area.

Background: The objective of this study was to determine the level of environmental contamination in hospitals in the Dutch/Belgian border area, using ATP measurements.

Design: A cross-sectional observational survey.

Methods: Standardized ATP measurements were conducted in 9 hospitals on 32 hospital wards.

Reducing transmission of methicillin-resistant in a surgical ward of a resource-limited hospital in Indonesia: an intervention study.

Background: Methicillin-resistant (MRSA) is endemic in healthcare settings in Indonesia.

Aim: To evaluate the effect of a bundle of preventive measures on the transmission and acquisition of MRSA in a surgical ward of a resource-limited hospital in Indonesia.

Methods: The study consisted of a pre-intervention (7 months), intervention (2 months), and post-intervention phase (5 months) and included screening for MRSA among eligible patients, healthcare workers (HCWs), and the hospital environment.

The relationship between reported domestic canine parvovirus cases and wild canid distribution.

Canine parvovirus (CPV) is an important and often fatal pathogen of domestic dogs. It is resistant in the environment and cross-species transmission has been indicated in some canid populations, but never in Australia. The aim of this study was to determine if an association exists between 1.

[Meningitis due to infection with Borrelia hispanica].

BACKGROUND Tick-borne relapsing fever is a disease that is caused by infection with a Borrelia bacterium, and is transmitted by ticks. This infectious disease is characterised by relapsing episodes of high fever, often accompanied by aspecific symptoms. CASE DESCRIPTION We describe the history of a 20-year-old woman who developed recurrent episodes of fever with headache and vomiting after a holiday in Morocco.

A further evaluation of picture prompts during auditory-visual conditional discrimination training.

This study was a systematic replication and extension of Fisher, Kodak, and Moore (2007), in which a picture prompt embedded into a least-to-most prompting sequence facilitated acquisition of auditory-visual conditional discriminations. Participants were 4 children who had been diagnosed with autism; 2 had limited prior receptive skills, and 2 had more advanced receptive skills. We used a balanced design to compare the effects of picture prompts, pointing prompts, and either trial-and-error learning or a no-reinforcement condition.