Publications by authors named "Arkadyi V Semke"
Article Synopsis
- The study investigates the role of muscarinic acetylcholine receptors in the development of tardive dyskinesia (TD) among patients with schizophrenia.
- Researchers analyzed data from 472 patients, looking at specific genetic variations in two muscarinic receptor genes and their association with TD symptoms, measured by the Abnormal Involuntary Movement Scale.
- They found a lower prevalence of a particular genetic variant in TD patients, suggesting a potential protective effect, although further analysis with other relevant factors showed that this association might not be statistically significant.
Background: Schizophrenia is a psychiatric disorder that affects approximately 0.4%-1% of the population worldwide. Diagnosis of schizophrenia is based primarily on Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria.
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