Publications by authors named "Arjun Ramaswamy"
Ramaswamy A, Kumar R, Ish P, Gupta N. Author Response. Indian J Crit Care Med 2024;28(4):405.
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- Monitoring the thickness of the parasternal intercostal muscles can provide important insights into a patient's ability to wean off mechanical ventilation.
- The study aimed to assess the effectiveness of parasternal intercostal muscle thickness fraction (PICTF%) as a predictor for weaning outcomes in patients who were intubated for over 48 hours.
- Results showed that a PICTF% of 15.38% or higher accurately predicted extubation failure, with a sensitivity of 75% and specificity of 87.8%.
How neural circuits develop in the human brain has remained almost impossible to study at the neuronal level. Here, we investigate human cortical neuron development, plasticity, and function using a mouse/human chimera model in which xenotransplanted human cortical pyramidal neurons integrate as single cells into the mouse cortex. Combined neuronal tracing, electrophysiology, and in vivo structural and functional imaging of the transplanted cells reveal a coordinated developmental roadmap recapitulating key milestones of human cortical neuron development.
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