Publications by authors named "Ariza M"

It has been estimated that ∼4% of individuals infected with SARS-CoV-2 will be diagnosed with post-COVID condition. Previous studies have evidenced the presence of cognitive dysfunction and structural brain changes in infected individuals; however, the relationship between structural changes and cognitive alterations in post-COVID condition is still not clear. Consequently, the aim of this work is to study structural brain alterations in post-COVID condition patients after almost 2 years of infection and their likely relationship with patients' cognitive impairment.

View Article and Find Full Text PDF

High-risk human papillomavirus (HR-HPV) and other sexually transmitted infections (STIs-O) are promoters to the development of cervical cancer (CC), especially when they co-exist. This study aims to determine the prevalence of the major STIs-O and the rate of co-infection in women previously diagnosed with HR-HPV infection. For this observational study, 254 women aged 25-65 years who were being followed up for HR-HPV infection (without a CC history) were recruited at a hospital's Gynaecology Department from February 2024 to November 2024.

View Article and Find Full Text PDF

In the current study, we aimed (i) to evaluate sleep quality via wrist actigraphy monitoring of nonhospitalized and hospitalized post-COVID-19 condition (PCC) participants; (ii) to correlate actigraphy measures with subjective measures of sleep quality, such as the Pittsburgh Sleep Quality Index (PSQI); and (iii) to investigate whether total sleep time or sleep efficiency could affect PCC cognitive performance. We included 49 individuals with PCC from the NAUTILUS Project (NCT05307549 and NCT05307575) who were monitored for 1 week via actigraphy and who were also assessed with a comprehensive neuropsychological battery and the PSQI. We found that there were significant differences between nonhospitalized PCCs and hospitalized PCCs in the number of awakenings.

View Article and Find Full Text PDF

Purpose: Genetic testing is required to confirm a diagnosis of familial chylomicronemia syndrome (FCS). We assessed the pathogenicity of variants identified in the FCS canonical genes to diagnose FCS cases.

Methods: 245 patients with severe hypertriglyceridemia underwent next-generation sequencing.

View Article and Find Full Text PDF

: Infections caused by multidrug-resistant (MDR)bacteria pose a significant public health threat by worsening patient outcomes, contributing to hospital outbreaks, and increasing health and economic burdens. Advanced genomic tools enhance the detection of resistance genes, virulence factors, and high-risk clones, thus improving the management of MDR infections. In the Autonomous Community of Aragon, the diversity and incidence of carbapenemase-producing Enterobacteriaceae (CPE) have increased during the last years.

View Article and Find Full Text PDF
Article Synopsis
  • - Studies have shown that individuals recovering from COVID-19 experience lower retinal vascular density and larger foveal avascular zones, with more severe cases exhibiting greater reductions in these measures.
  • - An observational study of 104 post-COVID-19 condition (PCC) participants found that those with severe COVID-19 had significantly worse retinal measurements and cognitive impairments compared to those with mild cases.
  • - The results indicate that retinal microvascular changes linked to severe COVID-19 are associated with cognitive deficits, suggesting that more severe infections can result in prolonged damage to both retinal and cognitive health.
View Article and Find Full Text PDF
Article Synopsis
  • - Participants in the MindFit Project, a study involving chronic stroke survivors, engaged in different intervention groups, including mindfulness-based stress reduction and physical exercise, to address their numerous physical, cognitive, and emotional challenges post-stroke.
  • - A qualitative study involving interviews with participants revealed that they found the interventions generally beneficial, with mindfulness helping emotional regulation, physical exercise boosting capabilities, and cognitive training aiding mental functions; the group environment provided peer support despite some challenges related to participant diversity.
  • - The findings underscore the complexity of stroke recovery and advocate for holistic, patient-centered rehabilitation strategies that integrate both physical and cognitive approaches, with remote delivery being a practical yet challenging option for survivors.
View Article and Find Full Text PDF

Introduction: Adults with Post-COVID-19 Condition (PCC) may show cognitive impairments in attention, processing speed, memory, and executive function. Multimodal programs that combine cognitive training, physical activity and emotional tasks, such as mindfulness-based interventions (MBIs), may offer a suitable alternative for improving PCC treatments. Immersive Virtual Reality (IVR) is a promising technology that can enhance traditional cognitive training, physical activity, and MBIs.

View Article and Find Full Text PDF

Objective: In the present study, we aimed to assess the cognition of post-COVID-19 condition (PCC) participants in relation to their subjective sleep quality (Pittsburgh Sleep Quality Index, PSQI) and to analyse possible moderators of this effect, such as quality of life (European Quality of Life-5 Dimensions, EQ-5D), fatigue (Chadler Fatigue Questionnaire, CFQ), cognitive reserve (Cognitive Reserve Questionnaire, CRC), and subjective cognitive complaints (Memory Failures of Everyday Questionnaire, MFE-30).

Methods: We included 373 individuals with PCC and 126 healthy controls (HCs) from the NAUTILUS Project (NCT05307549 and NCT05307575) who were assessed with a comprehensive neuropsychological battery and various questionnaires.

Results: We found that PCC participants with poor sleep quality had a 4.

View Article and Find Full Text PDF
Article Synopsis
  • - The study investigates extreme cases of hyperalphalipoproteinemia (HAE), where individuals possess very high HDL cholesterol levels, and aims to understand their cardiovascular risk factors.
  • - Among the 53 participants, dyslipidemia was the most common risk factor, but there were notable gender differences in other factors like hypertension, which was more prevalent in men.
  • - The results found that over half of the participants showed signs of subclinical atherosclerosis, with age, alcohol use, and smoking linked to plaque presence, while HDL-C levels didn't significantly influence cardiovascular health.
View Article and Find Full Text PDF

Background: Teleconsultation in the context of clinical laboratories is a valuable tool for the early detection of dyslipidemia and prevention of cardiovascular risk. Here, we describe a patient who was referred to the Lipid Unit of the Virgen Macarena Hospital due to an alert for severe hypertriglyceridemia through its teleconsultation program.

Case Presentation: A comprehensive clinical and biochemical study of the patient was carried out, and genetic testing was performed on the patient and his family.

View Article and Find Full Text PDF
Article Synopsis
  • Angiosperms are vital for ecosystems and human life, making it important to understand their evolutionary history to grasp their ecological dominance.
  • The study builds an extensive tree of life for about 8,000 angiosperm genera using 353 nuclear genes, significantly increasing the sampling size and refining earlier classifications.
  • The findings reveal a complex evolutionary history marked by high gene tree conflict and rapid diversification, particularly during the early angiosperm evolution, with shifts in diversification rates linked to global temperature changes.
View Article and Find Full Text PDF

The risk factors for post-COVID-19 cognitive impairment have been poorly described. This study aimed to identify the sociodemographic, clinical, and lifestyle characteristics that characterize a group of post-COVID-19 condition (PCC) participants with neuropsychological impairment. The study sample included 426 participants with PCC who underwent a neurobehavioral evaluation.

View Article and Find Full Text PDF

The study aimed to assess sleep quality in PCC patients and its predictors by analysing its relationship with emotional, cognitive and functional variables, as well as possible differences based on COVID-19 severity. We included 368 individuals with PCC and 123 healthy controls (HCs) from the NAUTILUS Project (NCT05307549 and NCT05307575). We assessed sleep quality (Pittsburgh Sleep Quality Index, PSQI), anxiety (Generalized Anxiety Disorder, GAD-7), depression (Patient Health Questionnaire, PHQ-9), global cognition (Montreal Cognitive Assessment, MoCA), everyday memory failures (Memory Failures of Everyday Questionnaire, MFE-30), fatigue (Chadler Fatigue Questionnaire, CFQ), quality of life (European Quality of Life-5 Dimensions, EQ-5D), and physical activity levels (International Physical Activity Questionnaire, IPAQ).

View Article and Find Full Text PDF

The red colour of most berries is often associated to fruit healthiness, since it has been linked to enrichment in anthocyanins (polyphenol with antioxidative properties). However, recent studies suggest that anthocyanins could not be the major contributors to bioactivity leading to uncertainty about their role as important molecules in the generation of health-promoting properties. To shed light on this issue, spectrophotometric and HPLC techniques were used for characterizing the content of phenolic compounds, including anthocyanins, in fruits of red (, cv.

View Article and Find Full Text PDF

Objective: A long-term decline in health-related quality of life (HRQoL) has been reported after coronavirus disease 2019 (COVID-19). Studies with people with persistent symptoms showed inconsistent outcomes. Cognition and emotion are important determinants in HRQoL, but few studies have examined their prognostic significance for HRQoL and functionality in post-COVID patients with persisting symptoms.

View Article and Find Full Text PDF

Background: Patients with chronic disease have become one of the major challenges for health and social protection systems in developed countries. Integrated care models (ICM) have demonstrably improved the quality of care of chronic patients. However, new models of integration need further evaluation of its effectiveness and outcomes.

View Article and Find Full Text PDF

Genome-wide association studies (GWAS) allow identifying genomic regions related to traits of economic importance in animals of zootechnical interest. The objective of this research was to conduct a genome-wide association study on meat quality traits using the Illumina OvineSNPs50 BeadChip array. The animals were sampled in the departments of Córdoba, Cesar, and Valle del Cauca.

View Article and Find Full Text PDF

Eye movement control is impaired in some neurological conditions, but the impact of COVID-19 on eye movements remains unknown. This study aims to investigate differences in oculomotor function and pupil response in individuals who suffer post-COVID-19 condition (PCC) with cognitive deficits. Saccades, smooth pursuit, fixation, vergence and pupillary response were recorded using an eye tracker.

View Article and Find Full Text PDF

Myalgic Encephalomyelitis/ Chronic Fatigue syndrome (ME/CFS) is a complex, debilitating, long-term illness without a diagnostic biomarker. ME/CFS patients share overlapping symptoms with long COVID patients, an observation which has strengthened the infectious origin hypothesis of ME/CFS. However, the exact sequence of events leading to disease development is largely unknown for both clinical conditions.

View Article and Find Full Text PDF

Primary hypocholesterolemia (or hypobetalipoproteinemia) is a rare disorder of lipoprotein metabolism that may be due to a polygenic predisposition or a monogenic disease. Among these, it is possible to differentiate between symptomatic and asymptomatic forms, in which, in the absence of secondary causes, the initial clinical suspicion is plasma ApoB levels below the 5th percentile of the distribution by age and sex. Here we describe the differential diagnosis of a case of asymptomatic hypocholesterolemia.

View Article and Find Full Text PDF
Article Synopsis
  • * A systematic review of 19 clinical trials revealed that certain GLP-1 RAs, like semaglutide and dulaglutide, effectively reduced stroke cases, while others showed improvements in cognitive function.
  • * Despite some positive findings, GLP-1 RAs haven't significantly impacted diabetic peripheral neuropathy, highlighting the need for further research to confirm these treatments' effectiveness in reducing neurological complications.
View Article and Find Full Text PDF

Patients with post-coronavirus disease 2019 (COVID-19) conditions typically experience cognitive problems. Some studies have linked COVID-19 severity with long-term cognitive damage, while others did not observe such associations. This discrepancy can be attributed to methodological and sample variations.

View Article and Find Full Text PDF

Background: Activity assays for lipoprotein lipase (LPL) are not standardised for use in clinical settings.

Objective: This study sought to define and validate a cut-off points based on a ROC curve for the diagnosis of patients with familial chylomicronemia syndrome (FCS). We also evaluated the role of LPL activity in a comprehensive FCS diagnostic workflow.

View Article and Find Full Text PDF

There is increasing evidence that put into question the classical dogma that the Epstein-Barr virus (EBV) exists in cells as either a lytic virus in which new progeny is produced or in a latent state in which no progeny is produced. Notably, a third state has now been described, known as the abortive-lytic phase, which is characterized by the expression of some immediate early (IE) and early (E) genes, but no new virus progeny is produced. While the function of these IE and E gene products is not well understood, several recent studies support the concept they may contribute to tumor promotion by altering the tumor microenvironment (TME).

View Article and Find Full Text PDF