Publications by authors named "Aristeidis Panagiotakis"
Article Synopsis
- Melanoma is a serious type of skin cancer that can spread quickly and make it tough to treat.
- Researchers studied two different melanoma cell lines to find out how they change and spread in the body.
- They used special techniques to look at the chemicals in the cells and discovered that certain chemicals are important for understanding how melanoma spreads, which could help in finding better ways to diagnose and treat it.
Background: Urothelial bladder cancer (UBC) is one of the cancers with the highest mortality rate and prevalence worldwide; however, the clinical management of the disease remains challenging. Metabolomics has emerged as a powerful tool with beneficial applications in cancer biology and thus can provide new insights on the underlying mechanisms of UBC progression and/or reveal novel diagnostic and therapeutic schemes.
Methods: A collection of four human UBC cell lines that critically reflect the different malignancy grades of UBC was employed; RT4 (grade I), RT112 (grade II), T24 (grade III), and TCCSUP (grade IV).