Publications by authors named "Arisa Mototake"
Front Neurosci
September 2016
Article Synopsis
- Addiction to alcohol is influenced by orexin-1-type receptors (OX1Rs), which are linked to increased alcohol consumption, particularly in specific brain regions.
- Inhibition of OX1Rs in the medial nucleus accumbens shell (mNAsh) significantly reduces alcohol intake in mice, while effects in the anterior insular cortex (aINS) are surprisingly minimal.
- Additionally, OX1R inhibition in the medial prefrontal cortex (mPFC) also decreases alcohol drinking, highlighting the importance of these receptors in certain brain areas for understanding addiction behaviors.
