Publications by authors named "Arindam Palodhi"
In India, Mizoram has the highest incidence of gastric cancer (GC) which might be associated with environmental factors such as diet, Helicobacter pylori (H.pylori) and Epstein-Barr virus (EBV) infections, and somatic genomic alterations. We performed PCR cum sequencing and fragment analysis for detection of H.
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- - Oropharyngeal cancer, common in Meghalaya, India, is linked to unique risks like smokeless tobacco and areca nut consumption, but its underlying genetic changes are not well understood.
- - This study analyzed DNA methylation and gene expression in oropharyngeal cancer patients, finding 194 silenced and 241 overexpressed genes, with key pathways related to immune responses and osteoclast differentiation significantly involved.
- - The research showed differences in DNA methylation and gene expression compared to other head and neck cancers, and no HPV DNA was found in the tumor samples, enhancing the understanding of oropharyngeal cancer.
Determination of the cause of inherited hemolysis is based on clinical and stepwise conventional laboratory tests. Patients with obscure etiology require genetic diagnosis, which is time-consuming, expensive, and laborious, mainly because of numerous causal genes. This study enrolled 43 patients with clinical and laboratory evidence of unexplained hemolytic anemia.
View Article and Find Full Text PDFWe have identified 164 somatic mutations in mitochondrial DNA in gingivobuccal oral cancer by deep sequencing the mitochondrial genome from paired tumor and blood DNA samples from 89 patients. We have found evidence of positive selection of somatic nonsynonymous mutations. Non-synonymous mutations in mitochondrial respiratory genes were found to increase the risk of lymph node metastasis (P = 0.
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