The RNA-Binding and RNA-Melting Activities of the Multifunctional Protein Nucleobindin 1.

Nucleobindin 1 (NUCB1) is a ubiquitous multidomain protein that belongs to the EF-hand Ca-binding superfamily. NUCB1 interacts with Galpha protein, cyclooxygenase, amyloid precursor protein, and lipids. It is involved in stress response and human diseases.

Two Epitope Regions Revealed in the Complex of IL-17A and Anti-IL-17A VH Domain.

Interleukin-17 (IL-17) is a cytokine produced by the Th17 cells. It is involved in chronic inflammation in patients with autoimmune diseases, such as rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, and psoriasis. The antibodies targeting IL-17 and/or IL-17R are therapy tools for these diseases.