Publications by authors named "Arina Plotnikova"
Temperature is a crucial regulator of the rate and direction of biochemical reactions and cell processes. The recent data indicating the presence of local thermal gradients associated with the sites of high-rate thermogenesis, on the one hand, demonstrate the possibility for the existence of "thermal signaling" in a cell and, on the other, are criticized on the basis of thermodynamic calculations and models. Here, we review the main thermometric techniques and sensors developed for the determination of temperature inside living cells and diverse intracellular compartments.
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- The study compared two wide field-of-view fluorescence imaging systems with different excitation wavelengths (405 nm and 635 nm) for diagnosing tumors.
- Both systems were tested on tumor phantoms as well as in six patients with basal cell carcinoma and oral mucosa cancer, confirming the ability to define lesion boundaries and fluorescence intensity.
- The 405 nm system outperformed the 635 nm system in distinguishing between tumor and healthy tissue for oral mucosal cancer, indicating greater effectiveness in eliminating background noise and providing consistent fluorescence quantification.