Publications by authors named "Arina C Hitzeroth"
Infectious coryza, an upper respiratory tract disease in chickens, caused by Avibacterium paragallinarum, leads to huge economic losses. The disease is controlled through vaccination; but vaccination efficacy is dependent on correct identification of the infecting serovar, as limited cross-protection is reported amongst some serovars. Current identification methods include the heamagglutination inhibition test, which is demanding and could be subjective.
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- Infectious coryza (IC) is a respiratory disease in chickens caused by Avibacterium paragallinarum, and this study focused on understanding the immune response in infected chickens.
- Gene expression profiling of 30 genes was performed on nasal samples from 11 chickens, including a control group, using real-time PCR for analysis.
- The findings indicated that the immune response is triggered by TLR4, leading to a Th2-dominant response and early production of inflammatory cytokines through the MyD88-dependent signaling pathway.