Design and validation of a MV/kV imaging-based markerless tracking system for assessing real-time lung tumor motion.

Purpose: Localizing lung tumors during treatment delivery is critical for managing respiratory motion, ensuring tumor coverage, and reducing toxicities. The purpose of this project is to develop a real-time system that performs markerless tracking of lung tumors using simultaneously acquired MV and kV images during radiotherapy of lung cancer with volumetric modulated arc therapy.

Method: Continuous MV/kV images were simultaneously acquired during dose delivery.