Publications by authors named "Arif Nm Ansori"
Infectious wounds on the skin surface are easily colonized by bacteria from pyogenic group that manifest as inflammation, such as is a Gram-negative bacterium and an opportunistic pathogen known for causing invasive state in critically ill and immunocompromised patients. The aim of this study was to detect the 16S rRNA and genes in using polymerase chain reaction (PCR) method. The sample in this study was pus isolate from a 5-year-old boy with leg wounds.
View Article and Find Full Text PDFMolecular interaction analysis of ferulic acid (4-hydroxy-3-methoxycinnamic acid) as main bioactive compound from palm oil waste against MCF-7 receptors: An in silico study.
Narra J
August 2024
Article Synopsis
- Ferulic acid, a phytochemical found in grains, fruits, and palm oil waste, was studied for its potential anticancer effects on breast cancer cell lines (MCF-7).
- The study utilized computational analysis, including molecular docking and dynamics simulations, to assess ferulic acid's interaction with specific breast cancer receptors, demonstrating significant binding affinity and optimal interaction with receptor 2IOG.
- The ADMET prediction indicated that ferulic acid possesses favorable properties for drug development, suggesting its potential as a therapeutic agent against breast cancer.
Diabetes is closely related to immune response problems when it occurs chronically. Pegagan () is a medicinal plant with active compounds. Madecassoside is beneficial in treating diabetes, and nanoparticle technology is expected to enhance the medicinal potential and availability of pegagan compounds.
View Article and Find Full Text PDFCRISPR-Cas9 has emerged as a revolutionary tool that enables precise and efficient modifications of the genetic material. This review provides a comprehensive overview of CRISPR-Cas9 technology and its applications in genome editing. We begin by describing the fundamental principles of CRISPR-Cas9 technology, explaining how the system utilizes a single guide RNA (sgRNA) to direct the Cas9 nuclease to specific DNA sequences in the genome, resulting in targeted double-stranded breaks.
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