Publications by authors named "Arif I Soykan"

Article Synopsis
  • Researchers aimed to improve the diagnosis of coeliac disease (CD) with mild mucosal changes by using a new monoclonal antibody to study T cell receptor (TCR)γδ intra-epithelial lymphocytes (IELs).
  • They analyzed 167 cases, including untreated CD and non-coeliac groups, and found that TCRγδ IEL levels were significantly higher in CD patients, correlating with mucosal damage severity.
  • The study proposes a diagnostic algorithm based on γδ IEL counts and ratios, which accurately classified most cases and could enhance histopathological diagnosis for coeliac disease.
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Article Synopsis
  • This study aimed to compare the occurrence of Helicobacter pylori infection in rheumatoid arthritis (RA) patients who experienced gastrointestinal intolerance due to methotrexate (MTX) and those who did not.
  • Out of 390 analyzed patients, 41% exhibited MTX-related gastrointestinal intolerance, with higher rates of H. pylori and inflammation found in that group.
  • Logistic regression showed that both the presence of H. pylori and the use of specific biologic medications were significantly linked to the gastrointestinal issues caused by MTX.
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Background: Coronavirus disease-2019 has become a serious pandemic, and still remains a risk despite vaccines that have been devel- oped. Among inflammatory bowel disease patients old age, inflammatory bowel disease activation, the existence of the comorbid dis- ease, and using steroids are known risk factors for severe coronavirus disease-2019. But there are different data for drugs other than corticosteroids used.

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