Publications by authors named "Arif Babul"

Artificial neural networks (ANNs) are showing increasing promise as decision support tools in medicine and particularly in neuroscience and neuroimaging. Recently, there has been increasing work on using neural networks to classify individuals with concussion using electroencephalography (EEG) data. However, to date the need for research grade equipment has limited the applications to clinical environments.

View Article and Find Full Text PDF

Concussion is a global health concern. Despite its high prevalence, a sound understanding of the mechanisms underlying this type of diffuse brain injury remains elusive. It is, however, well established that concussions cause significant functional deficits; that children and youths are disproportionately affected and have longer recovery time than adults; and that individuals suffering from a concussion are more prone to experience additional concussions, with each successive injury increasing the risk of long term neurological and mental health complications.

View Article and Find Full Text PDF

Children and youths are at a greater risk of concussions than adults, and once injured, take longer to recover. A key feature of concussion is an increase in functional connectivity, yet it remains unclear how changes in functional connectivity relate to the patterns of information flow within resting state networks following concussion and how these relate to brain function. We applied a data-driven measure of directed effective brain connectivity to compare the patterns of information flow in healthy adolescents and adolescents with subacute concussion during the resting state condition.

View Article and Find Full Text PDF

It is known that in many neurological disorders such as Down syndrome, main brain rhythms shift their frequencies slightly, and characterizing the spatial distribution of these shifts is of interest. This article reports on the development of a Skew-t mixed model for the spatial analysis of resting state brain activity in healthy controls and individuals with Down syndrome. Time series of oscillatory brain activity are recorded using magnetoencephalography, and spectral summaries are examined at multiple sensor locations across the scalp.

View Article and Find Full Text PDF

Interest in understanding the interplay between noise and the response of a nonlinear device cuts across disciplinary boundaries. It is as relevant for unmasking the dynamics of neurons in noisy environments as it is for designing reliable nanoscale logic circuit elements and sensors. Most studies of noise in nonlinear devices are limited to either time-correlated noise with a Lorentzian spectrum (of which the white noise is a limiting case) or just white noise.

View Article and Find Full Text PDF

In hierarchical cosmological models, galaxies grow in mass through the continual accretion of smaller ones. The tidal disruption of these systems is expected to result in loosely bound stars surrounding the galaxy, at distances that reach 10-100 times the radius of the central disk. The number, luminosity and morphology of the relics of this process provide significant clues to galaxy formation history, but obtaining a comprehensive survey of these components is difficult because of their intrinsic faintness and vast extent.

View Article and Find Full Text PDF