Clinical Characteristics and Care Trajectories of Transgender and Gender Diverse Patients With Cancer Seen in a Pediatric Gender Clinic.

Background: There is very little information on the experiences of transgender and gender diverse (TGD) youth with cancer.

Aims: To examine clinical characteristics and care trajectories of TGD youth a history of cancer.

Methods: This case series reviewed records of 2790 pediatric gender clinic patients seen between 2007 and 2022 to identify 14 with a history of cancer diagnosis.

Covariates of the Severity of Aggression in Sexual Crimes: Psychopathy and Borderline Characteristics.

Whereas risk assessment literature on sexual offending has primarily focused on prediction of subsequent sexual crimes, and not the severity of those crimes, the first aim of the present study was to identify variables that predict the amount of damage to victims in sexual crimes compared with those that predict general aggressiveness. The second aim was to ascertain whether adding emotional instability measurements, as in borderline personality disorder (BPD), would add incremental variance to that captured by the facets of the Psychopathy Checklist-Revised (PCL-R). Trained raters assessed on the PCL-R, BPD, and measures of severity of sexual and nonsexual violence 302 adults who had sexually offended.

Sex matters: females in proestrus show greater diazepam anxiolysis and brain-derived neurotrophin factor- and parvalbumin-positive neurons than males.

In humans and animal models, sex differences are reported for anxiety-like behavior and response to anxiogenic stimuli. In the current work, we studied anxiety-like behavior and response to the prototypical anti-anxiety drug, diazepam. We used 6th generation outbred lines of adult Long Evans rats with high and low anxiety-like behavior phenotypes to investigate the impact of proestrus on the baseline and diazepam-induced behavior.

Identity concealment in transgender adults: A qualitative assessment of minority stress and gender affirmation.

Minority individuals might conceal their identity in social contexts in an effort to avoid stigma and victimization. Unfortunately, identity concealment is thought to impact psychological distress in transgender and gender nonconforming (TGNC) individuals. Thus, through 30 in-depth interviews, we sought to understand if and how identity concealment was experienced by TGNC individuals.

The Relation of Familiarity With Sexual Abusers to Subsequent Developmental Adaptation in Youths Who Have Sexually Offended.

The present study explored the effects of child sexual abuse (CSA) on the adaptation of male juveniles who subsequently sexually offended (JSOs; n = 178; age, M = 16.05 years, SD = 0.27, range = 12-22).

Periodic maternal deprivation may modulate offspring anxiety-like behavior through mechanisms involving neuroplasticity in the amygdala.

Maternal care has been shown to affect the development of behavioral and endocrine systems. In rats, periodic maternal deprivation (PMD) serves as an early life stressor that directly influences maternal care by promoting more pup-directed behaviors in stressed dams. To further assess the qualities of PMD that may ameliorate long-term anxiety effects in trait anxiety animals, we coded behaviors across lactation (postnatal day (PND) 5, 16, 21) in dams phenotyped as high (HAn) and low-anxiety (LAn).