Publications by authors named "Ariel Dh Gewirtz"
Life Sci Alliance
August 2022
Article Synopsis
- eQTLs are genetic variations that influence gene expression, and traditional analyses often overlook the complexity of gene regulatory networks.
- The TBLDA framework is developed to analyze gene expression and genotype data together, accommodating multiple samples from individuals without losing accuracy.
- By applying this model to GTEx v8 data, the authors successfully identified thousands of eQTLs while capturing significant biological signals across different tissues, all using unnormalized raw count data.
