Early Bone Metastases are Associated with Worse Outcomes in Metastatic Urothelial Carcinoma.

Background: Outcomes of patients with metastatic urothelial carcinoma (mUC) with early bone metastases (eBM) vs no early bone metastases (nBM) have not thoroughly been described in the age of immuno-oncology.

Objective: To compare survival and other clinical outcomes in patients with eBM and nBM.

Methods: We used a multi-institutional database of patients with mUC treated with systemic therapy.

Epidemiology and outcomes of primary pediatric lung malignancies: Updates from the SEER database.

Background: Primary pediatric lung malignancies are rare tumors. We provide an updated analysis of the epidemiology and prognosis of these tumors since the last SEER series published in 2009.

Methods: The SEER 18 database from 1975 to 2016 was analyzed for patients ages 0-19 years with primary lung and/or bronchus neoplasms.