Publications by authors named "Arief Rahman Afief"
Multiple myeloma (MM) is a hematological malignancy. It is widely believed that genetic factors play a significant role in the development of MM, as investigated in numerous studies. However, the application of genomic information for clinical purposes, including diagnostic and prognostic biomarkers, remains largely confined to research.
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- Chickenpox is caused by the varicella-zoster virus (VZV), and it can lead to severe complications, including bacterial infections and neurological issues, regardless of risk factors.
- The study aimed to identify global genetic variants that contribute to susceptibility to chickenpox through bioinformatics, analyzing data from multiple genomic databases.
- Results showed that specific genetic variants associated with higher susceptibility are more common in European, American, and African populations compared to Asians, highlighting a potential connection between genetics and chickenpox severity.
Multiple sclerosis (MS) is a chronic autoimmune disease in the central nervous system (CNS) marked by inflammation, demyelination, and axonal loss. Currently available MS medication is limited, thereby calling for a strategy to accelerate new drug discovery. One of the strategies to discover new drugs is to utilize old drugs for new indications, an approach known as drug repurposing.
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