Publications by authors named "Aric B E Rininger"
Cancer Res Commun
May 2023
Article Synopsis
- - This study introduces a new spatial proteogenomic (SPG) assay on the GeoMx Digital Spatial Profiler platform, which allows for high-plex analysis of proteins (>100) and RNA (>18,000) from a single tissue sample.
- - The SPG assay shows high accuracy and reproducibility in analyzing human and mouse tissues, effectively distinguishing RNA and protein expressions in specific cell subpopulations within colorectal and lung cancers.
- - Examination of glioblastoma multiforme (GBM) using the SPG assay reveals distinct differences in protein and RNA profiles between giant cell GBM and typical GBM, emphasizing its potential for detailed spatial analysis of complex tumors.
