Publications by authors named "Arianna Morena"
Purpose: to evaluate the diagnostic accuracy of late iodine enhancement (LIE) in cardiac computed tomography (CCT) compared to late gadolinium enhancement (LGE) in cardiac magnetic resonance (CMR) for myocardial tissue characterization.
Materials And Methods: EMBASE, PubMed/MEDLINE, and CENTRAL were searched for studies reporting the accuracy of LIE with LGE as the gold standard of reference. QUADAS-2 tool was used to assess the risk of bias.
Article Synopsis
- The study evaluates the performance of ultrathin drug-eluting stents (DES) versus thin-strut DES and drug-eluting balloons (DEB) in treating in-stent restenosis (ISR) in patients.
- Results show that ultrathin DES significantly lowers the risk of adverse events, including cardiac death and need for revascularization, when compared to both thin-strut DES and DEBs after three years of follow-up.
- Additionally, in patients with diffuse ISR, ultrathin DES outperformed thin-strut DES in reducing risks of target lesion revascularization (TLR) and target vessel revascularization (TVR).
Spontaneous coronary artery dissection (SCAD) is a rare but significant cause of acute coronary syndrome (ACS), primarily affecting young women, often during pregnancy. Despite its rarity, SCAD poses challenges due to limited evidence on management strategies. This review examines the current state of art of SCAD management, integrating interventional and clinical insights from recent studies.
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- Beta-blockers play a key role in therapy after a heart attack (myocardial infarction), but their effectiveness for patients without reduced left ventricular function (LVEF) is under scrutiny.
- A study assessed how well patients with ST-segment elevation myocardial infarction (STEMI) adhered to beta-blocker medication after discharge, looking at the effects of adherence on health outcomes based on LVEF at discharge using data from 4,688 patients.
- Results showed that good adherence (≥80%) was linked to lower overall and heart-related deaths, particularly in patients with severely reduced LVEF (≤40%), but no significant benefit was observed in those with better LVEF.
Article Synopsis
- The study investigates the effectiveness of different coronary stents in patients at high bleeding risk (HBR) who require short-term antiplatelet therapy, finding that drug-eluting stents (DESs) are generally better than bare metal stents (BMSs).
- A network meta-analysis covering four trials with over 6,600 HBR patients showed that DESs reduced major adverse cardiovascular events (MACEs) and improved safety outcomes compared to BMSs, particularly with 1-month dual antiplatelet therapy.
- Among the DESs analyzed, the Orsiro stent ranked the highest for effectiveness, closely followed by Synergy, showing reduced rates of revascularization and stent thrombosis, which contributed
Article Synopsis
- The study investigates the effectiveness and safety of continuous percutaneous stellate ganglion block (C-PSGB) compared to thoracic epidural anesthesia (TEA) for treating refractory ventricular arrhythmias in patients with advanced heart disease.
- C-PSGB was performed on 26 patients, resulting in 59% experiencing complete suppression of arrhythmias and 94% showing overall clinical benefits, while TEA had higher side-effect-related discontinuation rates.
- Overall, the findings suggest that C-PSGB is a promising and safer alternative for managing these heart conditions, especially for patients on anticoagulation therapy.
Background: The impact of statin therapy on cardiovascular outcomes after ST-elevation acute myocardial infarction (STEMI) in real- world patients is understudied.
Aims: To identify predictors of low adherence and discontinuation to statin therapy within 6 months after STEMI and to estimate their impact on cardiovascular outcomes at one year follow-up.
Methods: We evaluated real-world adherence to statin therapy by comparing the number of bought tablets to the expected ones at 1 year follow-up through pharmacy registries.