UNC-33L partially rescues life span and locomotion defects in mutants but fails to rescue dauer formation defects.

Herein, we tested the ability of UNC-33L to rescue dauer formation, lifespan, and locomotion defects of mutants. Results show that the presence of UNC-33L does not rescue the defective dauer phenotype in mutants. However, UNC-33L significantly rescued premature death and uncoordinated locomotion in young adults.