Cystic fibrosis in Europe: improved lung function and longevity - reasons for cautious optimism, but challenges remain.

Background: Prognosis and disease severity in cystic fibrosis (CF) are linked to declining lung function. To characterise lung function by the number of adults in countries with different levels of Gross National Income (GNI), data from the European Cystic Fibrosis Society Patient Registry were utilised.

Methods: Annual data including age, forced expiratory volume in 1 s (FEV), anthropometry, genotype, respiratory cultures and CF-related diabetes (CFRD) were retrieved between 2011 and 2021.